TSDs completed or currently in progress


TSD 1: Introduction to evidence synthesis for decision making
TSD 2: A general linear modelling framework for pair-wise and network meta-analysis of randomised controlled trials
TSD 3: Heterogeneity: subgroups, meta-regression, bias and bias-adjustment
TSD 4: Inconsistency in networks of evidence based on randomised controlled trials 
TSD 5: Evidence synthesis in the baseline natural history model
TSD 6: Embedding evidence synthesis in probabilistic cost effectiveness analysis: software choices
TSD 7: Evidence synthesis of treatment efficacy in decision making: a reviewer’s checklist
TSD 8: An introduction to the measurement and valuation of health for NICE submissions
TSD 9: The identification, review and synthesis of health state utility values from the literature
TSD 10: The use of mapping methods to estimate health state utility values
TSD 11: Alternatives to EQ-5D for generating health state utility values
TSD 12: The use of health state utility values in decision models
TSD 13: Identifying and reviewing evidence to inform the conceptualisation and population of cost-effectiveness models
TSD 14: Survival analysis for economic evaluations alongside clinical trials – extrapolation with patient-level data
TSD 15:  Cost-effectiveness modelling using patient-level simulation
TSD 16: Adjusting survival time estimates in the presence of treatment switching
TSD 17: The use of observational data to inform estimates of treatment effectiveness in technology appraisal: Methods for comparative individual patient data
TSD 18:  Methods for population-adjusted indirect comparisons in submissions to NICE
TSD 19:  Partitioned Survival Analysis as a decision modelling tool


For more information on these documents, or to provide feedback, please contact the DSU Project Manager, Liz Metham.