TSDs completed or currently in progress

TSD 1:

Introduction to evidence synthesis for decision making

TSD 2:

A general linear modelling framework for pair-wise and network meta-analysis of randomised controlled trials

TSD 3:

Heterogeneity: subgroups, meta-regression, bias and bias-adjustment

TSD 4:

Inconsistency in networks of evidence based on randomised controlled trials 

TSD 5:

Evidence synthesis in the baseline natural history model

TSD 6:

Embedding evidence synthesis in probabilistic cost effectiveness analysis: software choices

TSD 7:

Evidence synthesis of treatment efficacy in decision making: a reviewer’s checklist

TSD 8:

An introduction to the measurement and valuation of health for NICE submissions

TSD 9:

The identification, review and synthesis of health state utility values from the literature

TSD 10:

The use of mapping methods to estimate health state utility values

TSD 11:

Alternatives to EQ-5D for generating health state utility values

TSD 12:

The use of health state utility values in decision models

TSD 13:

Identifying and reviewing evidence to inform the conceptualisation and population of cost-effectiveness models

TSD 14:

Survival analysis for economic evaluations alongside clinical trials – extrapolation with patient-level data

TSD 15: 

Cost-effectiveness modelling using patient-level simulation

TSD 16:

Adjusting survival time estimates in the presence of treatment switching

TSD 17:

The use of observational data to inform estimates of treatment effectiveness in technology appraisal: Methods for comparative individual patient data

TSD 18: 

Methods for population-adjusted indirect comparisons in submissions to NICE

TSD 19: 

Partitioned Survival Analysis as a decision modelling tool

TSD 20:

Multivariate meta-analysis of summary data for combining treatment effects on correlated outcomes and evaluating surrogate endpoints 


For more information on these documents, or to provide feedback, please contact the DSU Project Manager, Liz Metham.